Indicators of radioresistance modified by radioprotective agents report 1. delta. pO/sub 2/ as indicator of degree of mexamine-induced enhancement of radioresistance of rat bone marrow. [X rays]

Journal Article · Sun Jan 01 04:00:00 EST 1978 · Radiobiology (USSR) (Engl. Transl.); (United States)

OSTI ID:7025318

Rozhdestvenskii, L M; Nikolaeva, S I

The indicator approach to evaluation of effects of radioprotective agents is substantiated. A correlation was obtained between hypoxic and radioprotective effects of mexamine, given 5 min prior to irradiation, in rat bone marrow cells in vivo. An evaluation was made of both mean effectiveness of varying degrees of hypoxia and effectiveness in an individual animal on the basis of the DMF criterion.

• OSTI ID: 7025318
• Journal Information: Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 18:1; ISSN RADBA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINES
ANIMAL CELLS
ANIMALS
ANOXIA
AZOLES
BIOLOGICAL EFFECTS
BIOLOGICAL INDICATORS
BIOLOGICAL RADIATION EFFECTS
BODY
BONE MARROW
BONE MARROW CELLS
CONNECTIVE TISSUE CELLS
CORRELATIONS
DRUGS
ELECTROMAGNETIC RADIATION
ETHERS
EXTERNAL IRRADIATION
HEMATOPOIETIC SYSTEM
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
INDOLES
IONIZING RADIATIONS
IRRADIATION
MAMMALS
MEXAMINE
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
ORGANS
PYRROLES
RADIATION EFFECTS
RADIATIONS
RADIOPROTECTIVE SUBSTANCES
RADIOSENSITIVITY
RADIOSENSITIVITY EFFECTS
RATS
RESPONSE MODIFYING FACTORS
RODENTS
SEROTONIN
SOMATIC CELLS
SYMPATHOMIMETICS
TISSUES
TRYPTAMINES
VERTEBRATES
WHOLE-BODY IRRADIATION
X RADIATION