Lack of interaction between dietary fructose and zinc (Zn) nutriture in rats

Journal Article · Wed Mar 05 04:00:00 EST 1986 · Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States)

OSTI ID:7024476

Smith, J C; Failla, M L; Fields, M; Revett, K R; Rose, A

Dietary fructose, when compared to cornstarch, exacerbates copper deficiency. The purpose of this study was to determine whether Zn deficiency is similarly enhanced by high fructose intake. Seventy-five male SD rats were randomly assigned to one of the following diets containing 62% of the indicated carbohydrate: Zn deficient (0.6 ppm) X fructose; Zn deficient X starch; Zn supplemented (32 ppm) X fructose; Zn supplemented X starch. Animals were pair-fed to the Zn deficient X fructose group for 4 weeks. Survival, weight gain and tissue weight were also affected by dietary Zn, but not dietary carbohydrate. Dietary carbohydrate also failed to alter food intake of rats consuming Zn deficient diets. Unlike copper deficiency, the severity of Zn deficiency is not increased by feeding diets high in fructose compared to starch. The lack of a carbohydrate effect on zinc status indicates that the fructose-copper interaction is selective. This knowledge will facilitate the design of studies aimed at defining the mechanism(s) underlying fructose-trace element interaction.

• Research Organization: Dept. of Agriculture, Beltsville, MD
• OSTI ID: 7024476
• Report Number(s): CONF-8604222-
• Journal Information: Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States), Journal Name: Fed. Proc., Fed. Am. Soc. Exp. Biol.; (United States) Vol. 45:4; ISSN FEPRA
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOCHEMICAL REACTION KINETICS
CARBOHYDRATES
DIET
ELEMENTS
FRUCTOSE
HEXOSES
INTAKE
KETONES
KINETICS
MAMMALS
METALS
MONOSACCHARIDES
NUTRITIONAL DEFICIENCY
ORGANIC COMPOUNDS
POLYSACCHARIDES
RATS
REACTION KINETICS
REAGENTS
RODENTS
SACCHARIDES
STARCH
VERTEBRATES
WEIGHT
ZINC