Nuclear Medicine Program progress report for quarter ending March 31, 1990
The evaluation of the effects of albumin and albumin plus sodium palmitate in the phosphate buffer perfusate on the relative incorporation of 15-(p-(I-125)iodophenyl)-3-(R,S)-methylpentadecanoic acid (BMIPP) into endogenous lipids of isolated rat hearts has been studied. The effects of eluant salt character and concentration on the elution of (Re-188)perrhenate from the alumina-based tungsten-188/rhenium-188 generator system have also been investigated. During this period several agents were supplied to Medical Cooperative investigators, including (I-123)-labeled and (I-131)-labeled fatty acid analogues for studies at the Brookhaven National Laboratory and the Cardiology Department at the Free University of Amsterdam. Tungsten-188/rhenium-188 generators were supplied to the University of Massachusetts and the Center for Molecular Medicine and Immunology, in Newark, New Jersey. Osmium-191 was supplied for fabrication of generators for patient studies in Finland. 1 ref., 2 figs., 2 tabs.
- Research Organization:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
- Sponsoring Organization:
- DOE/ER
- DOE Contract Number:
- AC05-84OR21400
- OSTI ID:
- 7015943
- Report Number(s):
- ORNL/TM-11550; ON: DE90013608
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
ALBUMINS
BIOLOGICAL EFFECTS
MONOCARBOXYLIC ACIDS
IODINATION
RADIOPHARMACEUTICALS
SYNTHESIS
ABSORPTIVITY
ANTIBODIES
AQUEOUS SOLUTIONS
CHELATING AGENTS
HEART
IODINE 123
IODINE 131
NUCLEAR MEDICINE
PROGRESS REPORT
RADIOCHEMISTRY
RATS
RHENIUM 188
TUNGSTEN 188
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARBOXYLIC ACIDS
CARDIOVASCULAR SYSTEM
CHEMICAL REACTIONS
CHEMISTRY
DAYS LIVING RADIOISOTOPES
DISPERSIONS
DOCUMENT TYPES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
EVEN-EVEN NUCLEI
HALOGENATION
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MAMMALS
MEDICINE
MINUTES LIVING RADIOISOTOPES
MIXTURES
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
OPTICAL PROPERTIES
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
PHYSICAL PROPERTIES
PROTEINS
RADIOISOTOPES
RHENIUM ISOTOPES
RODENTS
SOLUTIONS
TUNGSTEN ISOTOPES
VERTEBRATES
550600* - Medicine
550500 - Metabolism