Stimulation of antibody formation through polypeptide thymic fraction (TP) in irradiated animals. [X radiation, rabbits]

Journal Article · Fri Feb 28 04:00:00 EDT 1975 · Ann. N.Y. Acad. Sci.; (United States)

DOI:https://doi.org/10.1111/j.1749-6632.1975.tb29086.x· OSTI ID:6952045

Milcu, S M; Potop, I; Boeru, V; Olinici, N

Total sublethal irradiation with x-rays of the rabbits immunized with the Salmonella TH 901 antigen induces a decrease in the serum antibody level as compared with nonirradiated controls. Administration of the polypeptide thymic (TP) extract to rabbits immunized with antigen and x-rayed in similar conditions produces a stimulation of antibody formation in these animals as compared to the nontreated controls. The level of antibodies is altered in the animals irradiated, and treatment with the TP extract shows that it has a protective effect on the organism.

• Research Organization: Institutul de Endocrinologie, Bucharest
• OSTI ID: 6952045
• Journal Information: Ann. N.Y. Acad. Sci.; (United States), Journal Name: Ann. N.Y. Acad. Sci.; (United States) Vol. 249; ISSN ANYAA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
ANTIBODY FORMATION
ANTIGENS
BACTERIA
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
ELECTROMAGNETIC RADIATION
IMMUNE REACTIONS
IONIZING RADIATIONS
MAMMALS
MICROORGANISMS
ORGANIC COMPOUNDS
PEPTIDES
POLYPEPTIDES
PROTEINS
RABBITS
RADIATION EFFECTS
RADIATIONS
SALMONELLA
VERTEBRATES
X RADIATION