Single photon Rb-82 imaging of remote myocardial infarction

Conference · Sun Jan 01 04:00:00 EST 1984 · J. Nucl. Med.; (United States)

OSTI ID:6930643

Ryan, J W; Harper, P V; Resnekov, H L; Stark, V

Rb-82, a short-lived (t 1/2 = 75 sec) positron emitting tracer which accumulates in the myocardium, is available from a long lived (t 1/2 = 25d) Sr-82 generator. Using a Pho-IV gamma camera and a rotating tungsten collimator, the authors have previously demonstrated the feasibility of single photon imaging of the myocardium with Rb-82 in subjects without myocardial defects on Tl-201 scans. To evaluate myocardial lesion detection with this technique the authors selected 10 patients with documented remote (>3 months) myocardial infarctions (MI) and imaged them at rest with both Tl-201 and Rb-82. After injection of 1.2 mCi Tl-201, 3 views (Ant, LAO 40, LAO 70) were obtained with a portable camera (LEM-Siemens). Subsequently, 2 views were chosen for Rb-82 imaging using 40 mCi i.v. per view. Images were accumulated from 2-7 minutes and compared to the Tl-201 images. In general, contrast was good with Rb-82 and interference from liver activity was minimal. In 1 patient the Tl-201 and Rb-82 images were normal. In 4 patients with inferior wall MI, the lesion site was abnormal in 4 with Tl-201 and in 3 with Rb-82. Both studies showed decreased activity at the site of the lesion in 5 patients with an MI in the LAD distribution. Although lesion detection was similar with both tracers, the defects in some cases were more visible with Rb-82 than Tl-201 and vice versa. Single photon imaging with Rb-82 provided lesion detection comparable with Tl-201 imaging in these patients with remote MI. Rb-82 imaging should prove especially useful in clinical situations such as acute MI in which rapid sequential myocardial perfusion imaging is desirable.

• Research Organization: The Univ. of Chicago, Chicago, IL
• OSTI ID: 6930643
• Report Number(s): CONF-840619-
• Conference Information: Journal Name: J. Nucl. Med.; (United States) Journal Volume: 25:5
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
ALKALI METAL ISOTOPES
ALKALINE EARTH ISOTOPES
ANTILEPTONS
ANTIMATTER
ANTIPARTICLES
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
CAMERAS
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COLLIMATORS
COMPUTERIZED TOMOGRAPHY
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DIGESTIVE SYSTEM
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTARY PARTICLES
EMISSION COMPUTED TOMOGRAPHY
EVEN-EVEN NUCLEI
FERMIONS
GAMMA CAMERAS
GLANDS
HEART
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
IMAGE PROCESSING
IMAGES
INJURIES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
LEPTONS
LIVER
MALFORMATIONS
MINUTES LIVING RADIOISOTOPES
MUSCLES
MYOCARDIAL INFARCTION
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
POSITRONS
PROCESSING
RADIOISOTOPES
RUBIDIUM 82
RUBIDIUM ISOTOPES
SECONDS LIVING RADIOISOTOPES
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
STRONTIUM 82
STRONTIUM ISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
TOMOGRAPHY
TRACER TECHNIQUES
USES