Planar positron imaging of rubidium-82 for myocardial infarction: A comparison with thallium-201 and regional wall motion

Journal Article · Fri Sep 01 04:00:00 EDT 1989 · American Heart Journal; (USA)

DOI:https://doi.org/10.1016/0002-8703(89)90277-9· OSTI ID:5470612

Williams, K A; Ryan, J W; Resnekov, L; Stark, V; Peterson, E L; Gustafson, G C; Martin, W B; Freier, P A; Harper, P V ^[1]

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1. Univ. of Chicago Pritzker School of Medicine, IL (USA)

Rubidium-82 (Rb-82) is a generator-produced, short half-life (76 seconds) positron emitting potassium analog. Using a mobile gamma camera equipped with a rotating tungsten collimator and high-energy shielding, we examined the use of Rb-82 in the coronary care unit and clinical laboratory for detection of perfusion defects due to myocardial infarction. We studied 31 subjects, 10 patients with acute myocardial infarction, 12 with remote myocardial infarction, and nine controls. Rb-82 images were compared with Tl-201 and regional wall motion for detection of infarct-related arteries. Of the 22 patients with myocardial infarction, 16 were identified with Rb-82 and Tl-201. In nine control subjects, eight were normal with each method. Correlation between Rb-82 and Tl-201 defect scores was excellent. Sensitivity and specificity for infarct-related arteries were similar for Rb-82, Tl-201, and wall motion imaging. Thus planar Rb-82 imaging can detect MI reliably in the coronary care unit and in the clinical laboratory.

• OSTI ID: 5470612
• Journal Information: American Heart Journal; (USA), Journal Name: American Heart Journal; (USA) Vol. 118:3; ISSN AHJOA; ISSN 0002-8703
• Country of Publication: United States
• Language: English

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550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ALKALI METAL ISOTOPES
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIOLOGICAL HALF-LIFE
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DOSES
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
HEART
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MINUTES LIVING RADIOISOTOPES
MYOCARDIAL INFARCTION
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
ORGANS
PATIENTS
POSITRON COMPUTED TOMOGRAPHY
RADIATION DOSES
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RUBIDIUM 82
RUBIDIUM ISOTOPES
SECONDS LIVING RADIOISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
TOMOGRAPHY