Feasibility of single photon tomography with RB-82

Conference · Sun Jan 01 04:00:00 EST 1984 · J. Nucl. Med.; (United States)

OSTI ID:7088230

Ryan, J W; Harper, P V; Chua, K G; Stark, V

Rb-82 (t 1/2 = 75 sec) is a positron emitting myocardial perfusion tracer available from a long lived (t 1/2 = 25d) Sr-82 generator. The authors have imaged Rb-82 in the single photon mode using a Pho-TV gamma camera with a parallel hole rotating tungsten collimator but only one view of the heart is obtained with each Rb-82 injection. For exercise studies with Rb-82, tomographic myocardial imaging is desirable. Because of the limited availability of ECT instrumentation, the clinical utilization of this tracer will be enhanced by the development of suitable instrumentation for imaging high energy photons in standard nuclear medicine units. A 7 pinhole collimator capable of imaging high energy photons was designed for an LFOV camera. It was built with thick shielding (2 1/2'' of lead) which largely preserved the geometry of the original system designed for low energy tracers and myocardial images obtained with N-13 ammonia were previously reported. Using 4mm pinhole inserts of tungsten, Rb-82 imaging was performed at rest in 4 male subjects after injection of tracer intravenously in doses up to 60 mCi. A commercially available software program for a DEC Gamma-11 which was designed to avoid exaggeration of lesions was used to reconstruct activity imaged from 2 - 7 minutes after injection. Tomographic sections of good quality were obtained. Sequential rest and exercise studies should be feasible with this technique of tomographic myocardial imaging. The short half life of the tracer also allows detection of changing patterns during the redistribution phase with serial injections after exercise.

• Research Organization: The Univ. of Chicago, Chicago, IL
• OSTI ID: 7088230
• Report Number(s): CONF-840619-
• Conference Information: Journal Name: J. Nucl. Med.; (United States) Journal Volume: 25:5
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ALKALI METAL ISOTOPES
ALKALINE EARTH ISOTOPES
AMMONIA
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
CAMERAS
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COLLIMATORS
COMPUTER CODES
COMPUTERIZED TOMOGRAPHY
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTARY PARTICLES
ELEMENTS
EMISSION COMPUTED TOMOGRAPHY
EVEN-EVEN NUCLEI
EXERCISE
GAMMA CAMERAS
HEART
HOURS LIVING RADIOISOTOPES
HYDRIDES
HYDROGEN COMPOUNDS
IMAGE PROCESSING
INJECTION
INTAKE
INTERMEDIATE MASS NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
MALES
MASSLESS PARTICLES
MEDICINE
METALS
MINUTES LIVING RADIOISOTOPES
MUSCLES
MYOCARDIAL INFARCTION
MYOCARDIUM
NITROGEN COMPOUNDS
NITROGEN HYDRIDES
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PHOTONS
PROCESSING
RADIOISOTOPES
RUBIDIUM 82
RUBIDIUM ISOTOPES
SHIELDING
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
STRONTIUM 82
STRONTIUM ISOTOPES
TOMOGRAPHY
TRACER TECHNIQUES
TRANSITION ELEMENTS
TUNGSTEN