Study of respiratory response of guinea pigs to oil mists
Journal Article
·
· Am. Ind. Hyg. Assoc. J.; (United States)
A study of respiratory response of guinea pigs to oil mists, including mists of laboratory-grade paraffin oil, light lubricating oil (neat and saturated with SO/sub 2/), an unused multigrade additive motor oil (neat and SO/sub 2/-saturated), and a used motor oil (neat and SO/sub 2/-saturated) supplied at 10, 40, 100, and 200 mg/cu m for one hour, showed that aerosols of these oils at < 200 mg/cu m are not short-term irritants, as monitored by pulmonary functions, and that there is no apparent relationship between pulmonary mechanics and the hydrocarbon structure, the presence of additives or combustion products, or saturation with sulfur dioxide. At >200 mg/cu m, both the reacted and unreacted light lubricating oil mists significantly reduced lung compliance. With the exception of the reacted light lubricating oil and the reacted used motor oil, all the exposures produced a slight increase in respiratory frequency, which appeared related to the stress of the exposure.
- OSTI ID:
- 6919956
- Journal Information:
- Am. Ind. Hyg. Assoc. J.; (United States), Journal Name: Am. Ind. Hyg. Assoc. J.; (United States) Vol. 40:8; ISSN AIHAA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
02 PETROLEUM
020600 -- Petroleum-- Health & Safety
04 OIL SHALES AND TAR SANDS
040700 -- Oil Shales & Tar Sands-- Health & Safety
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADDITIVES
AEROSOLS
ALKANES
ANIMALS
BIOLOGICAL EFFECTS
CHALCOGENIDES
COLLOIDS
DISPERSIONS
FUEL ADDITIVES
GUINEA PIGS
HYDROCARBONS
LUBRICANTS
LUBRICATING OILS
MAMMALS
MONITORING
OILS
ORGANIC COMPOUNDS
OTHER ORGANIC COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
PARAFFIN
PETROLEUM PRODUCTS
RESPIRATORY SYSTEM
RODENTS
SOLS
SULFUR COMPOUNDS
SULFUR DIOXIDE
SULFUR OXIDES
VERTEBRATES
WAXES
020600 -- Petroleum-- Health & Safety
04 OIL SHALES AND TAR SANDS
040700 -- Oil Shales & Tar Sands-- Health & Safety
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ADDITIVES
AEROSOLS
ALKANES
ANIMALS
BIOLOGICAL EFFECTS
CHALCOGENIDES
COLLOIDS
DISPERSIONS
FUEL ADDITIVES
GUINEA PIGS
HYDROCARBONS
LUBRICANTS
LUBRICATING OILS
MAMMALS
MONITORING
OILS
ORGANIC COMPOUNDS
OTHER ORGANIC COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
PARAFFIN
PETROLEUM PRODUCTS
RESPIRATORY SYSTEM
RODENTS
SOLS
SULFUR COMPOUNDS
SULFUR DIOXIDE
SULFUR OXIDES
VERTEBRATES
WAXES