Effect of oil mists on the irritancy of sulfur dioxide. II. Motor oil

Journal Article · Sat Sep 01 04:00:00 EDT 1979 · Am. Ind. Hyg. Assoc. J.; (United States)

DOI:https://doi.org/10.1080/15298667991430334· OSTI ID:5685241

Costa, D L; Amdur, M O

This study examines the effect of sub-micrometer aerosols of motor oil on the irritant potency of sulfur dioxide. The increase in pulmonary flow resistance in guinea pigs was used as the bioassay of irritant response. When administered simultaneously, both unused and used motor oil protected against the irritant response to sulfur dioxide. This protective effect was lost when the oils had been previously reacted with sulfur dioxide. The additives used in the motor oil provided an equivalent protection when dissolved in a mineral oil which alone did not protect. Pre-exposure to motor oil did not provide protection. Sulfur dioxide and motor oil given together as a pre-exposure provided protection against further exposure to sulfur dioxide.

• Research Organization: Harvard School of Public Health, Boston, MA
• OSTI ID: 5685241
• Journal Information: Am. Ind. Hyg. Assoc. J.; (United States), Journal Name: Am. Ind. Hyg. Assoc. J.; (United States) Vol. 40:9; ISSN AIHAA
• Country of Publication: United States
• Language: English

Related Subjects

02 PETROLEUM
020900 -- Petroleum-- Environmental Aspects
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BIOASSAY
BIOLOGICAL EFFECTS
BODY
CHALCOGENIDES
DATA
DATA FORMS
DOSE-RESPONSE RELATIONSHIPS
EXPERIMENTAL DATA
GUINEA PIGS
INFORMATION
ISOLATED VALUES
LUBRICANTS
LUBRICATING OILS
LUNGS
MAMMALS
NUMERICAL DATA
OILS
ORGANIC COMPOUNDS
ORGANS
OTHER ORGANIC COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
PETROLEUM PRODUCTS
REAGENTS
RESPIRATION
RESPIRATORY SYSTEM
RESPONSE MODIFYING FACTORS
RODENTS
SULFUR COMPOUNDS
SULFUR DIOXIDE
SULFUR OXIDES
TIME DEPENDENCE
TOLERANCE
TOXICITY
VERTEBRATES
WASTE OILS