Effect of oil mists on the irritancy of sulfur dioxide. I. Mineral oils and light lubricating oil

Journal Article · Wed Aug 01 04:00:00 EDT 1979 · Am. Ind. Hyg. Assoc. J.; (United States)

DOI:https://doi.org/10.1080/15298667991430154· OSTI ID:5615458

Costa, D L; Amdur, M O

The increase in pulmonary flow resistance in unanesthetized guinea pigs was used to assess the effect of sub-micrometer oil aerosols on the response to sulfur dioxide. At a concentration of about 10 mg/M/sup 3/ neither a medicinal grade mineral oil nor a light lubricating oil altered the response when given simultaneously with 1 or 10 ppM sulfur dioxide. The naphthenic medicinal oil at 100 mg/m/sup 3/ failed to protect against 50 ppM sulfur dioxide when administered simultaneously. A 30 minute pre-exposure, however, conferred complete protection. A paraffinic laboratory grade mineral oil conferred protection when given simultaneously but was less effective when the pre-exposure protocol was used.

• Research Organization: Harvard School of Public Health, Boston, MA
• OSTI ID: 5615458
• Journal Information: Am. Ind. Hyg. Assoc. J.; (United States), Journal Name: Am. Ind. Hyg. Assoc. J.; (United States) Vol. 40:8; ISSN AIHAA
• Country of Publication: United States
• Language: English

Related Subjects

02 PETROLEUM
020900 -- Petroleum-- Environmental Aspects
551000 -- Physiological Systems
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
ALKANES
ANIMALS
BIOLOGICAL EFFECTS
CHALCOGENIDES
COLLOIDS
COMPARATIVE EVALUATIONS
DISPERSIONS
ENERGY SOURCES
ENVIRONMENTAL EFFECTS
FOSSIL FUELS
FUELS
GUINEA PIGS
HYDROCARBONS
LUBRICANTS
MAMMALS
MINERAL OILS
OILS
ORGANIC COMPOUNDS
OTHER ORGANIC COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
PARTICLE SIZE
RESPIRATION
RESPONSE MODIFYING FACTORS
RODENTS
SIZE
SOLS
SULFUR COMPOUNDS
SULFUR DIOXIDE
SULFUR OXIDES
TOXICITY
VERTEBRATES