Skip to main content
OSTI.GOVU.S. Department of Energy Office of Scientific and Technical Information
U.S. Department of Energy
Office of Scientific and Technical Information
 

Regeneration of the liver at different periods of mononuclear infiltration induced by zymosan granules

Journal Article · · Bull. Exp. Biol. Med. (Engl. Transl.); (United States)
DOI:https://doi.org/10.1007/BF00799064· OSTI ID:6906846
; ;
The aim of this investigation was to discover how the liver,with areas of mononuclear infiltration, developing in response to activation of Kupffer cells (KC) by zymosan granules (ZG), regenerates. In the experiments, an intraperitoneal injection of 1 microCi of /sup 3/H-thymidine/g body weight was given to the mice 1 h before sacrifice. Proliferation of hepatocytes and regeneration of the liver were intensified most when partial resection of the liver (PRL) was performed at the peak of mononuclear infiltration of the liver, namely five days after injection of ZG. The data indicate that not only activated KC, but also areas of mononuclear infiltration potentiate hepatocyte regeneration.
Research Organization:
Institute of Clinical and Experimental Medicine, Acad. of Sci., Novasibirsk
OSTI ID:
6906846
Journal Information:
Bull. Exp. Biol. Med. (Engl. Transl.); (United States), Journal Name: Bull. Exp. Biol. Med. (Engl. Transl.); (United States) Vol. 99:3; ISSN BEXBA
Country of Publication:
United States
Language:
English

Similar Records

Proliferation of the intestinal epithelium and of the regenerating liver of rats with epidermal growth factor deficiency
Journal Article · Mon Sep 01 00:00:00 EDT 1986 · Bull. Exp. Biol. Med. (Engl. Transl.); (United States) · OSTI ID:5563537
Bacterial clearance in the intact and regenerating liver
Journal Article · Thu Aug 01 00:00:00 EDT 1985 · J. Pediatr. Surg.; (United States) · OSTI ID:6179419
Autoradiographic analysis of hepatocytes in mirex-induced adaptive liver growth
Journal Article · Fri Jul 01 00:00:00 EDT 1988 · American Journal of Physiology; (USA) · OSTI ID:6896348

Related Subjects

550301* -- Cytology-- Tracer Techniques
550501 -- Metabolism-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ACID PHOSPHATASE
ANIMAL CELLS
ANIMAL TISSUES
ANIMALS
AZINES
BIOLOGICAL EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REGENERATION
BODY
CELL PROLIFERATION
DIGESTIVE SYSTEM
ENZYME ACTIVITY
ENZYMES
ESTERASES
GLANDS
HETEROCYCLIC COMPOUNDS
HYDROLASES
INJECTION
INTAKE
INTRAPERITONEAL INJECTION
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
LIVER
LIVER CELLS
MAMMALS
METABOLIC ACTIVATION
METABOLISM
MICE
NUCLEOSIDES
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PHOSPHATASES
PYRIMIDINES
RECOVERY
RETENTION
RETICULOENDOTHELIAL SYSTEM
RIBOSIDES
RODENTS
SOMATIC CELLS
STIMULATION
THYMIDINE
TISSUES
TRACER TECHNIQUES
TRITIUM COMPOUNDS
VERTEBRATES
ZYMOSAN