Mutagenicity testing of high performance liquid chromatography fractions from wood stove emission samples using a modified Salmonella assay requiring smaller sample volumes

Journal Article · Sun Jan 01 04:00:00 EST 1984 · Environ. Mutagen.; (United States)

DOI:https://doi.org/10.1002/em.2860060111· OSTI ID:6902894

Alfheim, I; Becher, G; Hongslo, J K; Ramdahl, T

Organic extracts of emissions from wood combustion have been fractionated by high performance liquid chromatography (HPLC) into 25-28 fractions. Each fraction was tested for mutagenic activity in a modified Ames Salmonella/microsome bioassay requiring one-third of the test volumes needed for the usual test. Direct mutagenic activity was noted predominantly in the most polar fractions, whereas indirect mutagenic activity was associated with the fractions containing polycyclic aromatic hydrocarbons (PAH) and with polar fractions probably consisting of aza-arenes and aromatic amines.

• Research Organization: Central Inst. for Industrial Research, Oslo, Norway
• OSTI ID: 6902894
• Journal Information: Environ. Mutagen.; (United States), Journal Name: Environ. Mutagen.; (United States) Vol. 6:1; ISSN ENMUD
• Country of Publication: United States
• Language: English

Related Subjects

29 ENERGY PLANNING, POLICY, AND ECONOMY
299003* -- Energy Planning & Policy-- Unconventional Sources & Power Generation-- Other-- (-1989)
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102 -- Chemical & Spectral Procedures
APPLIANCES
AROMATICS
BACTERIA
CHROMATOGRAPHY
GASEOUS WASTES
HYDROCARBONS
LIQUID COLUMN CHROMATOGRAPHY
MICROORGANISMS
MUTAGEN SCREENING
ORGANIC COMPOUNDS
POLYCYCLIC AROMATIC HYDROCARBONS
SALMONELLA
SALMONELLA TYPHIMURIUM
SCREENING
SEPARATION PROCESSES
STOVES
VOLUME
WASTES
WOOD BURNING APPLIANCES