Mutagenicity testing of high performance liquid chromatography fractions from wood stove emission samples using a modified Salmonella assay requiring smaller sample volumes

Journal Article · Sun Jan 01 04:00:00 EST 1984 · Environ. Mutagen.; (United States)

DOI:https://doi.org/10.1002/em.2860060111· OSTI ID:6609503

Alfheim, I; Becher, G; Hongslo, J K; Ramdahl, T

Organic extracts of emissions from wood combustion have been fractionated by high performance liquid chromatography (HPLC) into 25-28 fractions. Each fraction was tested for mutagenic activity in a modified Ames Salmonella/microsome bioassay requiring one-third of the test volumes needed for the ususal test. Direct mutagenic activity was noted predominantly in the most polar fractions, whereas indirect mutagenic activity was associated with the fractions containing polycyclic aromatic hydrocarbons (PAH) and with polar fractions probably consisting of aza-arenes and aromatic amines.

• Research Organization: Central Inst. for Industrial Research, Oslo, Norway
• OSTI ID: 6609503
• Journal Information: Environ. Mutagen.; (United States), Journal Name: Environ. Mutagen.; (United States) Vol. 6:1; ISSN ENMUD
• Country of Publication: United States
• Language: English

Related Subjects

500200* -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
560302 -- Chemicals Metabolism & Toxicology-- Microorganisms-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINES
APPLIANCES
AROMATICS
AZAARENES
BACTERIA
CHROMATOGRAPHY
ECOLOGICAL CONCENTRATION
FRACTIONATION
FURNACES
GASEOUS WASTES
HETEROCYCLIC COMPOUNDS
HYDROCARBONS
LIQUID COLUMN CHROMATOGRAPHY
MICROORGANISMS
MUTAGEN SCREENING
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
POLYCYCLIC AROMATIC HYDROCARBONS
SALMONELLA
SCREENING
SEPARATION PROCESSES
WASTES
WOOD BURNING APPLIANCES
WOOD BURNING FURNACES