Comparison of performances of standard low energy collimators and a medium energy collimator specially designed for imaging with I-123
The use of iodine 123 produced via the Te-124 (rho,2n)I-123 rection is readily available and less expensive than (rho,5n) I-123. The use of standard collimators with (rho,2n) I-123 results in poor image quality due to a high percentage of photons with energies greater than 159 KeV resulting from I-124 contamination. A High Resolution Medium Energy (HR-ME) collimator has been developed to improve image quality and evaluated. LSF were measured at a depth of 20,60 and 100 mm using source inside a plexiglas phantom, 200 mm high, placed at 100 mm from the colimator and compared to results of Low Energy High Resolution (LE-HR) and Low Energy General Purpose (LE-GP) collimators. Sources consisted of rho,5n and rho,2n I-123. The latter used at 10 and 24 h EOB. Septal penetration was estimated by recording the spectrum at 80% window. The results show that FWHM and FWTM of the LE collimators are always smaller than the ME collimator with all sources. The FWHM and FWTM for each collimator increased with (rho,5n) I-123 and (rho,2n)I-123 10 h and 24 h after EOB, respectively. The ME collimator reduces septal penetration and minimizes the difference between spectra. It gives better results than the LE-HR collimator up to frequency 0.28 cycles/cm for rho,5n and up to 0.39 cycles/cm for rho,2n I-123. The MTF of the ME collimator are equal to or better than those of the LE-GP collimator at all frequencies. Although the results of the (rho,2n)10h EOB are better than the (rho,2n) 24 h EOB the differences are not significant. The authors conclude that the ME collimator improves the quality of (rho,2n) I-123 for both static and tomographic imaging and it could be used for In-111 imaging.
- Research Organization:
- Institut Gustave Roussy, Villejuif and CEA-ORIS
- OSTI ID:
- 6868505
- Report Number(s):
- CONF-840619-
- Journal Information:
- J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 25:5; ISSN JNMEA
- Country of Publication:
- United States
- Language:
- English
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550602 -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
651720 -- Nuclear Properties & Reactions
A=90-149
Experimental
73 NUCLEAR PHYSICS AND RADIATION PHYSICS
BARYON REACTIONS
BARYONS
BETA DECAY RADIOISOTOPES
CHARGED-PARTICLE REACTIONS
COLLIMATORS
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTARY PARTICLES
ENERGY RANGE
FERMIONS
HADRON REACTIONS
HADRONS
HOURS LIVING RADIOISOTOPES
IMAGE PROCESSING
INDIUM 111
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KEV RANGE
KEV RANGE 100-1000
MASSLESS PARTICLES
MINUTES LIVING RADIOISOTOPES
NEUTRONS
NUCLEAR REACTIONS
NUCLEI
NUCLEON REACTIONS
NUCLEONS
ODD-EVEN NUCLEI
PERFORMANCE TESTING
PHOTONS
PROCESSING
PROTON REACTIONS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESOLUTION
TARGETS
TELLURIUM 124 TARGET
TESTING
TOMOGRAPHY