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Performance of collimators used for tomographic imaging of I-123 contaminated with I-124

Journal Article · · J. Nucl. Med.; (United States)
OSTI ID:5234360
; ;

Iodine-123 prepared from the /sup 124/Te(p,2n)/sup 123/I reaction is contaminated with between 3% to 5% I-124 when imaging is performed. The effects of such a mixture were evaluated for medium-energy and low energy general-purpose collimators on a commerically available ratating gamma camera equipped to perform tomography. The planar sensitivity for I-123 was less for the general- purpose collimator, varying between 0.84 and 0.85 in water relative to that measured for the medium energy-collimator. Counts due to scattering or septal penetration of I-124 photons were greater for the general-purpose collimator (36%) than for the medium-energy collimator (15%). Evaluation of the higher-frequency components of the modulation transfer functions confirmed that the low-energy general-purpose collimator is expected to offer significantly more contrast information at frequencies above 0.21 cycles/cm. This is expected to contribute to image quality when studies are performed with collimators of similar design.

Research Organization:
Harvard Medical School, Boston, MA
OSTI ID:
5234360
Journal Information:
J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 24:11; ISSN JNMEA
Country of Publication:
United States
Language:
English

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Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
CAMERAS
COLLIMATORS
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
GAMMA CAMERAS
HOURS LIVING RADIOISOTOPES
IMAGES
IMPURITIES
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE 124
IODINE ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MOCKUP
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
PERFORMANCE
PHANTOMS
RADIOISOTOPES
RADIOPHARMACEUTICALS
STRUCTURAL MODELS
TOMOGRAPHY