Comparison of low- and medium-energy collimators for SPECT imaging with iodine-123-labeled antibodies
Journal Article
·
· J. Nucl. Med.; (United States)
OSTI ID:5008207
The planar and single photon emission computed tomography (SPECT) imaging performance of two low-energy and one medium-energy collimators has been compared for /sup 123/I(p,5n). Septal penetration in the low-energy collimators affected the planar uniformity and sensitivity and made the usual uniformity correction methods inappropriate. SPECT uniformity and resolution were also distorted by these artifacts induced in the planar images obtained with the low-energy collimators. The planar and SPECT images of a SPECT phantom contradicted the spatial resolution measurements made with a line source in air. The medium-energy collimator is recommended for imaging /sup 123/I(p,5n)-labeled antibodies in patients, particularly when quantitation is required.
- Research Organization:
- Univ. of California Davis Medical Center, Sacramento
- OSTI ID:
- 5008207
- Journal Information:
- J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 9; ISSN JNMEA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANTIBODIES
BETA DECAY RADIOISOTOPES
COLLIMATORS
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
HOURS LIVING RADIOISOTOPES
IMAGES
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MOCKUP
NUCLEI
ODD-EVEN NUCLEI
PHANTOMS
RADIOISOTOPES
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
STRUCTURAL MODELS
TOMOGRAPHY
62 RADIOLOGY AND NUCLEAR MEDICINE
ANTIBODIES
BETA DECAY RADIOISOTOPES
COLLIMATORS
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
HOURS LIVING RADIOISOTOPES
IMAGES
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MOCKUP
NUCLEI
ODD-EVEN NUCLEI
PHANTOMS
RADIOISOTOPES
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
STRUCTURAL MODELS
TOMOGRAPHY