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Biological effects of 15 MeV neutrons

Journal Article · · Int. J. Radiat. Oncol., Biol. Phys.; (United States)
;
To study the RBE of 15 MeV neutrons for normal tissues, the responses of jejunal crypt cells, lung, and esophagus to 15 MeV neutrons generated from a deuterium-tritium neutron generator were compared with responses to /sup 137/Cs (cesium) ..gamma..- or 300 kVp x-rays in the mouse. For jejunal crypt cell survival, the RBE was 1.5 at a survival of 10 crypt cells per circumference. The RBE for pulmonary lethal dose LD/sub 50/160/ and esophageal LD/sub 50/28/ was 1.2 and 3.02, respectively. Data available in the literature on the effects of 15 MeV neutrons on tumor and normal tissues were reviewed; additional studies which should be performed prior to the clinical use of 15 MeV deuterium-tritium neutron generators are suggested.
Research Organization:
Univ. of California, San Francisco
OSTI ID:
6844798
Journal Information:
Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 1:11-12; ISSN IOBPD
Country of Publication:
United States
Language:
English

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Related Subjects

560121 -- Radiation Effects on Cells-- External Source-- (-1987)
560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METAL ISOTOPES
ANIMAL CELLS
ANIMALS
BARYONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CESIUM 137
CESIUM ISOTOPES
COMPARATIVE EVALUATIONS
CRYOGENIC FLUIDS
CRYPT CELLS
DIGESTIVE SYSTEM
DOSE-RESPONSE RELATIONSHIPS
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
ELEMENTS
ENERGY RANGE
ESOPHAGUS
EXTERNAL IRRADIATION
FAST NEUTRONS
FERMIONS
FLUIDS
GAMMA RADIATION
HADRONS
IN VITRO
IONIZING RADIATIONS
IRRADIATION
ISOTOPES
LUNGS
MAMMALS
MEV RANGE
MEV RANGE 10-100
MICE
NEUTRONS
NONMETALS
NUCLEI
NUCLEONS
ODD-EVEN NUCLEI
ORGANS
OXYGEN
PARTIAL BODY IRRADIATION
RADIATION EFFECTS
RADIATIONS
RADIOISOTOPES
RADIOSENSITIVITY EFFECTS
RBE
RESPIRATORY SYSTEM
RODENTS
SOMATIC CELLS
TUMOR CELLS
VERTEBRATES
WHOLE-BODY IRRADIATION
X RADIATION
YEARS LIVING RADIOISOTOPES