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Iodine contrast medium sensitizes cultured mammalian cells to x rays but not to. gamma. rays

Journal Article · · Radiat. Res.; (United States)
DOI:https://doi.org/10.2307/3575225· OSTI ID:6758420
The influence of an iodine contrast medium on several responses to radiation was examined in mammalian cells in culture (L5178Y). The presence of the medium at the time of irradiation enhanced cell killing, frequency of micronuclei, and yield of DNA single-strand breaks induced by x rays, depending on the concentration used, whereas no such effect was found with ..gamma.. rays. It was concluded that the contrast medium sensitizes mammalian cells in culture primarily by means of the photoelectric effect, thereby increasing the absorbed dose of x rays in the cells.
Research Organization:
National Inst. of Radiological Sciences, Chiba-shi, Japan
OSTI ID:
6758420
Journal Information:
Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 84:1; ISSN RAREA
Country of Publication:
United States
Language:
English

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