Experience with and potential of Cf-252 therapy for other tumors: Lexington clinical trials

Journal Article · Wed Jan 01 00:00:00 EST 1986 · Nucl. Sci. Appl.; (United States)

OSTI ID:6708381

Maruyama, Y

Clinical observations of tumor response in a variety of sites to Cf-252 (Cf) neutron brachytherapy (NT) are described. Many tumors which are accessible and easily implanted are suitable for Cf-NT, but in advanced stages, must be integrated into a more comprehensive program of local, regional and systemic therapy. With local tumor clearance and control, there should be treatment for regional disease using conventional photon radiotherapy; adjuvant therapies for disseminated disease using systemic therapy is also needed. While potential for therapy exists for Cf-NT treatment of many tumors, additional clinical trials carried out in a variety of global settings are needed where different tumors are common and are available for studies. Tumors suitable for study include e.g. cervix, uterus, vagina, tonsil-oropharynx, anterior oral cavity, prostate, female urethra, nasopharynx, anus and rectum, malignant glioma, parotid, perhaps esophagus, bladder, non-oat cell lung, localized sarcoma and melanoma, etc.

• Research Organization: Radiation Therapy Oncology Center, Univ. of Kentucky Medical Center, Lexington, KY
• OSTI ID: 6708381
• Journal Information: Nucl. Sci. Appl.; (United States), Vol. 2:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CALIFORNIUM 252
THERAPEUTIC USES
NEOPLASMS
NEUTRON THERAPY
CLEARANCE
KENTUCKY
MEDICAL ESTABLISHMENTS
PERFORMANCE TESTING
PHOTONS
RADIATION SOURCE IMPLANTS
RESEARCH PROGRAMS
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
CALIFORNIUM ISOTOPES
DISEASES
ELEMENTARY PARTICLES
EVEN-EVEN NUCLEI
FEDERAL REGION IV
HEAVY NUCLEI
IMPLANTS
ISOTOPES
MASSLESS PARTICLES
MEDICINE
NORTH AMERICA
NUCLEAR MEDICINE
NUCLEI
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
TESTING
THERAPY
USA
USES
YEARS LIVING RADIOISOTOPES
550603* - Medicine- External Radiation in Therapy- (1980-)
550604 - Medicine- Unsealed Radionuclides in Therapy- (1980-)