The effects of alternating magnetic fields on the survival of cultured mammalian cells irradiated with californium-252 and cobalt-60

Journal Article · Wed Jan 01 04:00:00 EST 1986 · Nucl. Sci. Appl.; (United States)

OSTI ID:6705531

Schroy, C B; Blue, J W; Goud, S N; Magura, C; Feola, J M; Maruyama, Y; Beach, J L

An alternating magnetic field (0.05T peak flux density at 1.92 kHz) was applied to cultured Chinese hamster cells in suspension during exposure to californium-252 (1.88 gy/h) or cobalt-60 (54 Gy/h). There was no increase in cell killing observed (assayed by colony formation) but there was slight evidence for a radioprotective effect. It is hypothesized that increasing the event size distribution by spiraling recoil protons around magnetic field lines adds no lethality to the short, dense ionization tracks produced by Cf-252 exposure. A comparison of the control curves for the conditions stated showed an RBE of 2.6 for Cf-252 (compared to Co-60) at the 10% survival level.

• Research Organization: Cleveland Clinic Foundation, Dept. of Radiation Therapy, Cleveland, OH
• OSTI ID: 6705531
• Journal Information: Nucl. Sci. Appl.; (United States), Journal Name: Nucl. Sci. Appl.; (United States) Vol. 2:3; ISSN NSAPD
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
560162 -- Radionuclide Effects
Kinetics
& Toxicology-- Animals
Plants
Microorganisms
& Cells
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
ANIMAL CELLS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOASSAY
BIOLOGICAL EFFECTS
CALIFORNIUM 252
CALIFORNIUM ISOTOPES
CELL CULTURES
CELL KILLING
CHO CELLS
COBALT 60
COBALT ISOTOPES
COLONY FORMATION
COMPARATIVE EVALUATIONS
DOSES
EVEN-EVEN NUCLEI
FLUX DENSITY
FREQUENCY RANGE
HEAVY NUCLEI
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZATION
IRRADIATION
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KHZ RANGE
KHZ RANGE 01-100
LETHAL DOSES
MAGNETIC FIELDS
MAGNETIC FLUX
MEASURING INSTRUMENTS
MINUTES LIVING RADIOISOTOPES
NEUTRON DETECTORS
NUCLEI
ODD-ODD NUCLEI
PROTON RECOIL DETECTORS
RADIATION DETECTORS
RADIATION PROTECTION
RADIOISOTOPES
RBE
SURVIVAL CURVES
YEARS LIVING RADIOISOTOPES