Clinical committee report: Recommendation for further clinical trials-patient studies
The Cf-252 (Cf) neutron brachytherapy (NT) trials should continue to explore the feasibility of Cf-NT treatment of a variety of bulky human cancers. Results hitherto from the USA (Lexington), Japan, USSR, and England justify trials on a research basis. The term ''bulky'' is imprecise and in future studies should be specified by measurement. U.S. Department of Energy and other suppliers need to be advised to fabricate Cf-252 sources in more appropriate sizes, strengths and configurations for clinical therapy. Study of facility design and development should continue with special attention to: 1) treatment centers, 2) afterloading devices, 3) automated/robotics and other specialized equipment for handling Cf-252, 4) shields and shielding material, 5) controlled duration treatments, 6) necessary specialized equipment for conducting Cf-NT trials and 7) safety for personnel. In addition to the aforementioned, the report makes recommendations in several other areas such as doses and schedules, randomized trials, and records.
- Research Organization:
- Emeritus Consultant, Churchill Hospital, Oxford
- OSTI ID:
- 6698536
- Journal Information:
- Nucl. Sci. Appl.; (United States), Vol. 2:3
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
CALIFORNIUM 252
THERAPEUTIC USES
NEOPLASMS
NEUTRON THERAPY
FEASIBILITY STUDIES
HUMAN POPULATIONS
JAPAN
KENTUCKY
PERFORMANCE TESTING
RADIATION DOSES
RESEARCH PROGRAMS
UNITED KINGDOM
USSR
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALPHA DECAY RADIOISOTOPES
ASIA
CALIFORNIUM ISOTOPES
DISEASES
DOSES
EASTERN EUROPE
EUROPE
EVEN-EVEN NUCLEI
FEDERAL REGION IV
HEAVY NUCLEI
ISOTOPES
MEDICINE
NORTH AMERICA
NUCLEAR MEDICINE
NUCLEI
POPULATIONS
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
TESTING
THERAPY
USA
USES
WESTERN EUROPE
YEARS LIVING RADIOISOTOPES
550603* - Medicine- External Radiation in Therapy- (1980-)
550604 - Medicine- Unsealed Radionuclides in Therapy- (1980-)