Neutron brachytherapy for the treatment of malignant neoplasia

Journal Article · Thu Dec 01 00:00:00 EST 1988 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(88)90238-6· OSTI ID:6609383

Maruyama, Y

In the 1930's both neutrons and the cyclotron were discovered, developed and used almost immediately for neutron beam therapy. Cf-252 was discovered in 1950 but its potential for cancer therapy was not postulated until 1965. Early sporadic clinical trials were used to treat only a few patients. The recognition of its curative properties and usefulness for bulky localized and radioresistant cancer therapy was not made until recently. In 1985, the Lexington Workshop led to a sharing of independent experiences from the USA, Japan, and the USSR; early trial experiences were related to neutron beam results. Localized neutron therapy using brachytherapy methods was found effective against radioresistance and bulky tumors. However, it needed to be used properly and with full appreciation of clinical oncology and the role of photon adjuvant therapy.

• Research Organization: Univ. of Kentucky Medical Center, Lexington (USA)
• OSTI ID: 6609383
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 15:6
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
NEOPLASMS
NEUTRON THERAPY
EFFICIENCY
HISTORICAL ASPECTS
JAPAN
NEUTRONS
USA
USSR
ASIA
BARYONS
DISEASES
EASTERN EUROPE
ELEMENTARY PARTICLES
EUROPE
FERMIONS
HADRONS
MEDICINE
NORTH AMERICA
NUCLEAR MEDICINE
NUCLEONS
RADIOLOGY
RADIOTHERAPY
THERAPY
550604* - Medicine- Unsealed Radionuclides in Therapy- (1980-)