The human interleukin-1 receptor antagonist (IL1RN) gene is located in the chromosome 2q14 region

Journal Article · Fri Jan 01 04:00:00 EST 1993 · Genomics; (United States)

DOI:https://doi.org/10.1006/geno.1993.1025· OSTI ID:6697347

Patterson, D; Jones, C; Hart, I; Bleskan, J; Berger, R; Geyer, D ^[1]; Eisenberg, S P ^[2]; Smith, Jr, M F; Arend, W P ^[3]

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1. Eleanor Roosevelt Institute for Cancer Research, Denver, CO (United States)
2. Synergen Inc., Boulder, CO (United States)
3. Univ. of Colorado Health Sciences Center, Denver (United States)

The gene for human interleukin-1 receptor antagonist (IL1RN) has been assigned to chromosome 2 on the basis of Southern blot analysis of a series of human-Chinese hamster cell hybrids. Using a yeast artificial chromosome containing the IL1RN gene as a probe, the human IL1RN gene was localized to the long arm of chromosome 2 at band 2q14.2 by fluorescence in situ hybridization. This site is near the positions of genes for human IL-l[alpha], IL-1[beta], and types I and II IL-1 receptors, as reported by other laboratories. 23 refs., 1 fig., 1 tab.

• OSTI ID: 6697347
• Journal Information: Genomics; (United States), Journal Name: Genomics; (United States) Vol. 15:1; ISSN GNMCEP; ISSN 0888-7543
• Country of Publication: United States
• Language: English

Related Subjects

550400* -- Genetics
59 BASIC BIOLOGICAL SCIENCES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CHROMOSOMES
FLUORESCENCE
GENES
GENETIC MAPPING
GROWTH FACTORS
HUMAN CHROMOSOME 2
HUMAN CHROMOSOMES
HYBRIDIZATION
LEUKOCYTES
LUMINESCENCE
LYMPHOKINES
MAPPING
MATERIALS
MEMBRANE PROTEINS
MITOGENS
ORGANIC COMPOUNDS
PROTEINS
RECEPTORS