Intra-operative Iodine-125 prostatic implant following bilateral pelvic lymphadenectomy

Journal Article · Tue May 01 00:00:00 EDT 1984 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(84)90298-0· OSTI ID:6657228

Kwong, E W.H.; Huh, S H; Nobler, M P; Smith, H S

Sixty-five patients with prostatic adenocarcinoma Stages B and C were treated with intraoperative Iodine-125 prostatic implantation following bilateral pelvic lymphadenectomy. Pelvic nodal metastases were found in 31% of the patients. All the patients have been followed for a period of 1 1/2 to 6 years. Serial digital rectal examination revealed complete regression of the palpable disease in 15% of the patients at 6 months, 47% at 1 year, and 87% at 2 years. Post-operative complications were also evaluated: 13% of the patients became sexually impotent, 11% had impaired potency after the procedure, and 26% of patients complained of dry ejaculation; and 17% developed scrotal and/or penile swelling, which persisted up to 14 months, but usually subsided within 5 months. Two patients developed local recurrence.

• Research Organization: Beth Israel Medical Center, New York, NY
• OSTI ID: 6657228
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 10:5
• Country of Publication: United States
• Language: English

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