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Radiation therapy in adenocarcinoma of the prostate with pelvic lymph node involvement on lymphadenectomy

Journal Article · · Int. J. Radiat. Oncol., Biol. Phys.; (United States)
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From 1970 to 1978, 135 of 429 patients with adenocarcinoma of the prostate (31%) had pelvic lymph nodal involvement at the time of bilateral pelvic lymphadenectomy and Iodine-125 interstitial implantation of the prostate at Memorial Sloan-Kettering Cancer Center. Postoperative external irradiation was given in 28 patients to the whole pelvis alone or with the para-aortic region. Determinate 5 year survival was 54% with (7/13) and without (13/24) external irradiation. Of 123 patients with 6 months to 7 years of follow-up, 31 (25%) with local control of the primary tumor developed distant metastases, mainly osseous, and 20 (16%) had local recurrence or persistence with or without distant spread.

Research Organization:
Memorial Sloan-Kettering Cancer Center, New York, NY
OSTI ID:
6866050
Journal Information:
Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 6:2; ISSN IOBPD
Country of Publication:
United States
Language:
English

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Related Subjects

550603 -- Medicine-- External Radiation in Therapy-- (1980-)
550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
560151* -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CARCINOMAS
DATA
DAYS LIVING RADIOISOTOPES
DISEASES
EDEMA
ELECTRON CAPTURE RADIOISOTOPES
EXPERIMENTAL DATA
GLANDS
IMPLANTS
INFORMATION
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPES
LUNGS
MALE GENITALS
MEDICINE
MORTALITY
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
NUMERICAL DATA
ODD-EVEN NUCLEI
ORGANS
PATHOLOGICAL CHANGES
PROSTATE
RADIATION EFFECTS
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
RESPIRATORY SYSTEM
SIDE EFFECTS
SURVIVAL CURVES
SYMPTOMS
THERAPY
URINARY TRACT