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Bilateral pelvic lymphadenectomy, iridium 192 template, and external beam therapy for localized prostatic carcinoma: complications and results

Journal Article · · South. Med. J.; (United States)
; ; ;

Thirty-five patients with prostatic adenocarcinoma were treated by bilateral pelvic lymphadenectomy and temporary implantation of iridium 192 strands with adjuvant external beam radiotherapy. With the implant the prostate received between 3200 and 3500 gray (Gy) followed in two weeks by small-field external beam irradiation for an additional dose of approximately 3400 Gy. Morbidity included an ileofemoral thrombosis in one patient, and transient radiation proctitis in four patients; one patient required transurethral prostatic resection for obstruction at one year. Local response of the primary tumor was dramatic in every case at three-month follow-up. In 11 of 15 patients (73%), biopsy at one year showed no evidence of disease.

Research Organization:
Medical College of Virginia, Richmond
OSTI ID:
5469307
Journal Information:
South. Med. J.; (United States), Journal Name: South. Med. J.; (United States) Vol. 81:1; ISSN SMJOA
Country of Publication:
United States
Language:
English

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Related Subjects

550600 -- Medicine
550603* -- Medicine-- External Radiation in Therapy-- (1980-)
560151 -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CARCINOMAS
DAYS LIVING RADIOISOTOPES
DIGESTIVE SYSTEM DISEASES
DISEASES
DOSES
ELECTRON CAPTURE RADIOISOTOPES
GLANDS
HEAVY NUCLEI
IMPLANTS
INJURIES
INTERNAL CONVERSION RADIOISOTOPES
IRIDIUM 192
IRIDIUM ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MALE GENITALS
MEDICINE
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
PATIENTS
PELVIS
PROCTITIS
PROSTATE
RADIATION DOSES
RADIATION EFFECTS
RADIATION INJURIES
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SURGERY
THERAPY
YEARS LIVING RADIOISOTOPES