Effects of short-term exposures to sulfuric acid and ammonium sulfate aerosols upon bronchial airway function in the donkey

Journal Article · Sat Apr 01 04:00:00 EST 1978 · Am. Ind. Hyg. Assoc. J.; (United States)

DOI:https://doi.org/10.1080/0002889778507759· OSTI ID:6639041

Schlesinger, R B; Lippmann, M; Albert, R E

The effects of one-hour inhalation exposures to 0.3 to 0.6 ..mu..m H/sub 2/SO/sub 4/ and (NH/sub 4/)/sub 2/SO/sub 4/ aerosols in the donkey were studied in terms of alterations in pulmonary flow resistance and dynamic compliance, and changes in the regional deposition and tracheobronchial mucociliary clearance of an inert test aerosol. Short-term slowing of clearance followed certain single exposures to H/sub 2/SO/sub 4/ at 194 to 1364 ..mu..g/m/sup 3/ in three of four animals, while two of the four demonstrated a more persistent slowing of their clearance. These exposure levels produced no measurable change in resistance, compliance or regional deposition. Exposures to (NH/sub 4/)SO/sub 4/ up to approximately 2000 ..mu..g/m/sup 3/ had no measurable effect upon resistance, compliance, regional deposition or mucociliary clearance.

• Research Organization: New York Univ., NY
• OSTI ID: 6639041
• Journal Information: Am. Ind. Hyg. Assoc. J.; (United States), Journal Name: Am. Ind. Hyg. Assoc. J.; (United States) Vol. 39:4; ISSN AIHAA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
AMMONIUM COMPOUNDS
AMMONIUM SULFATES
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL FUNCTIONS
BODY
BRONCHI
CLEARANCE
COLLOIDS
DISPERSIONS
EXCRETION
HYDROGEN COMPOUNDS
INDUSTRIAL MEDICINE
INHALATION
INORGANIC ACIDS
INTAKE
LUNG CLEARANCE
LUNGS
MAMMALS
MEDICINE
ORGANS
OXYGEN COMPOUNDS
RESPIRATORY SYSTEM
SOLS
SULFATES
SULFUR COMPOUNDS
SULFURIC ACID
VERTEBRATES