Chromosomal alterations as markers of exposure and effect
Conference
·
OSTI ID:6578000
The principles involved in the formation of chromosomal aberrations and sister chromatid exchanges are reviewed and their use as biological indicators of mutations or other induced cytogenetic damage discussed. The discussion centers on the use of human cells, specifically lymphocytes, in bioassays of mutagens and carcinogens. 28 references, 2 figures. (ACR)
- Research Organization:
- Lawrence Livermore National Lab., CA (USA)
- DOE Contract Number:
- W-7405-ENG-48
- OSTI ID:
- 6578000
- Report Number(s):
- UCRL-90724; CONF-840772-1; ON: DE84015633
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560301* -- Chemicals Metabolism & Toxicology-- Cells-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOASSAY
BIOLOGICAL INDICATORS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARCINOGENESIS
CHROMOSOMAL ABERRATIONS
CONNECTIVE TISSUE CELLS
LEUKOCYTES
LYMPHOCYTES
MAMMALS
MAN
MATERIALS
MUTAGENESIS
MUTATIONS
PATHOGENESIS
PRIMATES
SISTER CHROMATID EXCHANGES
SOMATIC CELLS
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOASSAY
BIOLOGICAL INDICATORS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARCINOGENESIS
CHROMOSOMAL ABERRATIONS
CONNECTIVE TISSUE CELLS
LEUKOCYTES
LYMPHOCYTES
MAMMALS
MAN
MATERIALS
MUTAGENESIS
MUTATIONS
PATHOGENESIS
PRIMATES
SISTER CHROMATID EXCHANGES
SOMATIC CELLS
VERTEBRATES