Inhibition of interferon-. cap alpha. /. beta. induction by crystalline cadmium sulfide
Journal Article
·
· Environ. Res.; (United States)
OSTI ID:6486821
The induction of interferon-..cap alpha../..beta.. by Newcastle disease virus in L-929 cells was inhibited by pretreatment of the cell cultures with the crystalline form of cadmium sulfide. As little as 10 ..mu..g/ml of crystalline cadmium sulfide was sufficient to inhibit the induction of interferon. Cell viability was not affected by this treatment as measured by trypan blue dye-exclusion viability staining. Between 6 and 24 hr of preincubation with crystalline cadmium sulfide was required for significant inhibition of interferon induction.
- Research Organization:
- Univ. of Louisville, KY
- OSTI ID:
- 6486821
- Journal Information:
- Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 42:1; ISSN ENVRA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CADMIUM
CADMIUM COMPOUNDS
CADMIUM SULFIDES
CELL CULTURES
CHALCOGENIDES
DISEASES
ELEMENTS
GROWTH FACTORS
IMMUNE REACTIONS
INFECTIOUS DISEASES
INHIBITION
INORGANIC PHOSPHORS
INTERFERON
L CELLS
LYMPHOKINES
METALS
MICROORGANISMS
MITOGENS
NEWCASTLE DISEASE
ORGANIC COMPOUNDS
PARASITES
PHOSPHORS
PROTEINS
SULFIDES
SULFUR COMPOUNDS
TOXICITY
VIABILITY
VIRAL DISEASES
VIRUSES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CADMIUM
CADMIUM COMPOUNDS
CADMIUM SULFIDES
CELL CULTURES
CHALCOGENIDES
DISEASES
ELEMENTS
GROWTH FACTORS
IMMUNE REACTIONS
INFECTIOUS DISEASES
INHIBITION
INORGANIC PHOSPHORS
INTERFERON
L CELLS
LYMPHOKINES
METALS
MICROORGANISMS
MITOGENS
NEWCASTLE DISEASE
ORGANIC COMPOUNDS
PARASITES
PHOSPHORS
PROTEINS
SULFIDES
SULFUR COMPOUNDS
TOXICITY
VIABILITY
VIRAL DISEASES
VIRUSES