Information profiles on potential occupational hazards: benzoin

Technical Report · Sun Mar 01 04:00:00 EST 1981

OSTI ID:6471999

Information on potential occupational hazards from exposure to benzoin was reviewed. Topics discussed included chemical and physical properties, production, uses, manufacturers and distributors, manufacturing processes, occupational exposure, and biological effects. The annual production of benzoin is approximately 90,000 pounds per year with an historical growth rate of about 6% per year. In carcinogenesis studies, the incidence of lymphomas and leukemia in dosed male rats increased with dose level, but not significantly. Mice demonstrated a significant increase in the incidence of lymphomas and leukemias at low dose levels. Bioassays have indicated that benzoin is not carcinogenic to male or female F344-rats or B6C3F1-mice. No evidence of mutagenicity, teratogenicity, or reproductive effects was found in animal studies. Allergic contact dermatitis has been reported in humans.

• Research Organization: Syracuse Research Corp., NY (USA). Center for Chemical Hazard Assessment
• OSTI ID: 6471999
• Report Number(s): PB-87-174629/XAB; SRC-TR-81-521
• Country of Publication: United States
• Language: English

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54 ENVIRONMENTAL SCIENCES
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99 GENERAL AND MISCELLANEOUS
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HAZARDOUS MATERIALS
INDOOR AIR POLLUTION
INDUSTRIAL MEDICINE
INDUSTRY
INSPECTION
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