Clearance by the rat of inhaled fly ash from fluidized-bed coal combustion

Journal Article · Thu Jan 01 04:00:00 EST 1981 · J. Toxicol. Environ. Health; (United States)

DOI:https://doi.org/10.1080/15287398109529963· OSTI ID:6459588

Griffis, L C; Snipes, M B; Brooks, A L

Fly ash from a fluidized-bed coal combustor was neutron-activated and administered to male Fischer 344 rats by a single nose-only inhalation exposure. The activated fly ash contained /sup 46/Sc and smaller amounts of other gamma-emitting radionuclides. Whole-body clearance of radioactivity of 127 d was described by an exponential equation, with the long-term component having a biological half-life of 78 d. High-resolution gamma spectra of the lungs was obtained with a Ge(Li) detector and the relative activities of several fly ash constituents were compared. The activities of /sup 152/Eu, /sup 134/Cs, /sup 54/Mn, and /sup 60/Co significantly decreased with time relative to those of /sup 46/Sc and /sup 59/Fe. These results indicate that the clearance of fly ash is similar to that of other relatively insoluble particles and that some elements may have been preferentially dissolved from the fly ash particles in vivo.

• Research Organization: Lovelace Inhalation Toxicology Research Institute, Albuquerque, NM
• DOE Contract Number: AC04-76EV01013
• OSTI ID: 6459588
• Journal Information: J. Toxicol. Environ. Health; (United States), Journal Name: J. Toxicol. Environ. Health; (United States) Vol. 7:1; ISSN JTEHD
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACTIVATION ANALYSIS
AEROSOL WASTES
ALKALI METAL ISOTOPES
ANIMALS
ASHES
BARYONS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIOLOGICAL HALF-LIFE
BIOLOGICAL MODELS
BODY
CARBONACEOUS MATERIALS
CESIUM 134
CESIUM ISOTOPES
CHEMICAL ANALYSIS
CHEMICAL REACTIONS
CLEARANCE
COAL
COBALT 60
COBALT ISOTOPES
COMBUSTION
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTARY PARTICLES
ENERGY SOURCES
ENVIRONMENTAL EFFECTS
EUROPIUM 152
EUROPIUM ISOTOPES
EVEN-ODD NUCLEI
EXCRETION
FERMIONS
FLUIDIZED-BED COMBUSTION
FLY ASH
FOSSIL FUELS
FUELS
HADRONS
HOURS LIVING RADIOISOTOPES
IN VIVO
INHALATION
INTAKE
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IRON 59
IRON ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
LUNG CLEARANCE
LUNGS
MAMMALS
MANGANESE 54
MANGANESE ISOTOPES
MATERIALS
MINUTES LIVING RADIOISOTOPES
NEUTRONS
NUCLEI
NUCLEONS
ODD-ODD NUCLEI
ORGANS
OXIDATION
PARTICLES
RADIOISOTOPES
RADIONUCLIDE KINETICS
RARE EARTH ISOTOPES
RARE EARTH NUCLEI
RATS
RESIDUES
RESPIRATORY SYSTEM
RODENTS
SCANDIUM 46
SCANDIUM ISOTOPES
SECONDS LIVING RADIOISOTOPES
THERMOCHEMICAL PROCESSES
TRACER TECHNIQUES
VERTEBRATES
WASTES
YEARS LIVING RADIOISOTOPES