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Immobilization of Aspergillus beta-glucosidase on Chitosan

Journal Article · · Appl. Environ. Microbiol.; (United States)
OSTI ID:6336357

..beta..-Glucosidase of Aspergillus phoenicis QM 329 was immobilized on chitosan, using the bifunctional agent glutaraldehyde. The most active preparation based on the amount of support contained a 1 : 2.5 enzyme-to-chitosan ratio (wt/wt). However, the specific activity of the bound enzyme decreased from 10 to 1% with increasing enzyme-to-chitosan ratio. Compared with free ..beta..-glucosidase, the immobilized enzyme exhibited: (1) a similar pH optimum but more activity at lower pH values; (2) improved thermal stability; (3) a similar response to inhibition by glucose; and (4) mass transfer limitations as reflected by higher apparent K/sub m/ and lower energy of activation.

Research Organization:
Army Natick Research and Development Command, Natick, MA
OSTI ID:
6336357
Journal Information:
Appl. Environ. Microbiol.; (United States), Journal Name: Appl. Environ. Microbiol.; (United States) Vol. 35:4; ISSN AEMID
Country of Publication:
United States
Language:
English