Effect of dietary fat on plasma glutathione peroxidase levels and intestinal absorption of /sup 75/Se-labeled sodium selenite in chicks
The effect of dietary fat on the availability of selenium was investigated in chicks fed either 4 or 20% butter, olive oil, rape oil, corn oil or sunflower oil in the diet for 3 weeks after hatching. Plasma glutathione peroxidase (GSH-Px) activity was used as an indicator of the body selenium status. In addition, the intestinal absorption of sodium selenite (/sup 75/Se-labeled) was determined by using both the in vivo ligated loop procedure and oral administration of the isotope. The plasma GSH-Px levels increased with increasing proportion of the polyunsaturated fatty acids in the diet. Increasing the amount of fat from 4 to 20% significantly enhanced the GSH-Px activity in the groups receiving butter or olive oil, but had no effect in animals fed the unsaturated fats. The absorption of (/sup 75/Se)selenite from the ligated duodenal loops tended to be reduced in chicks fed corn oil or sunflower oil as compared to the animals receiving butter in their diet. On the other hand, the type of dietary fat did not appear to affect the absorption of the orally administered selenite. The present study demonstrates that the type of dietary fat can affect the plasma GSH-Px levels in chicks without altering the intestinal absorption of selenite. However, the results on the absorption of the intraduodenally injected sodium selenite suggest that dietary fat plays some role in the intestinal transport of selenium.
- Research Organization:
- Univ. of Helsinki, Finland
- OSTI ID:
- 6307534
- Journal Information:
- J. Nutr.; (United States), Vol. 114:5
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
BUTTER FAT
BIOLOGICAL EFFECTS
CORN OIL
OLIVE OIL
PEROXIDASES
ENZYME ACTIVITY
SELENITES
INTESTINAL ABSORPTION
SELENIUM 75
CHICKENS
DIET
GLUTATHIONE
ORAL ADMINISTRATION
TRACER TECHNIQUES
ABSORPTION
ANIMALS
BETA DECAY RADIOISOTOPES
BIRDS
CARBOXYLIC ACIDS
DAYS LIVING RADIOISOTOPES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
ENZYMES
ESTERS
EVEN-ODD NUCLEI
FATS
FOWL
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
INTERMEDIATE MASS NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
LIPIDS
NUCLEI
OILS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
OTHER ORGANIC COMPOUNDS
OXIDOREDUCTASES
OXYGEN COMPOUNDS
PEPTIDES
POLYPEPTIDES
PORPHYRINS
PROTEINS
RADIOISOTOPES
RADIOPROTECTIVE SUBSTANCES
SELENIUM COMPOUNDS
SELENIUM ISOTOPES
TRIGLYCERIDES
UPTAKE
VEGETABLE OILS
VERTEBRATES
550201* - Biochemistry- Tracer Techniques