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The repair of potentially lethal and sublethal damage in unfed plateau-phase cultures irradiated at 0. 78 Gy/hr. [/sup 137/Cs]

Journal Article · · Radiat. Res.; (United States)
DOI:https://doi.org/10.2307/3575931· OSTI ID:6300954
Unfed plateau-phase cultures of Chinese hamster ovary (CHO) cells were irradiated at 0.78 Gy/hr to determine if accumulation and repair of sublethal and/or potentially lethal damage diminished as a function of small multiple doses and whether culture age affected repair. The repair of both potentially lethal and sublethal lesions was unaffected by aging or absorbed dose. Furthermore, repair of potentially lethal damage was associated with a decrease in the linear parameter of the equation - ln s = ..cap alpha..D + ..beta..D/sup 2/, suggesting that lesions produced by this process can be repaired.
Research Organization:
Columbia Univ., New York
DOE Contract Number:
AC02-78EV04733
OSTI ID:
6300954
Journal Information:
Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 92:3; ISSN RAREA
Country of Publication:
United States
Language:
English