Attenuation of radiation- and drug-induced conditioned taste aversions following area postrema lesions in the rat

Journal Article · Tue Feb 01 04:00:00 EST 1983 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3575994· OSTI ID:6219218

Rabin, B M; Hunt, W A; Lee, J

The effects of lesions of the area postrema on the acquisition of radiation- and drug-induced (histamine and lithium chloride) conditioned taste aversions were investigated. The results indicated that area postrema lesions caused a significant attenuation of the aversion produced by pairing a novel sucrose solution with radiation (100 rad) or drug injection. Further, the area postrema lesions produced a similar level of attenuation of the taste aversion in all three treatment conditions. The results are discussed in terms of the implications of this finding for defining the mechanisms by which exposure to ionizing radiation can lead to the acquisition of a conditioned taste aversion.

• Research Organization: Behavioral Sciences Department, Armed Forces Radiobiology Research Institute, Bethesda, Maryland
• OSTI ID: 6219218
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 93:2; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AMINES
ANIMALS
AVOIDANCE
AZOLES
BEHAVIOR
BIOLOGICAL EFFECTS
BIOLOGICAL PATHWAYS
BIOLOGICAL RADIATION EFFECTS
BODY
CONDITIONED REFLEXES
DOSES
FLAVOR
HETEROCYCLIC COMPOUNDS
HISTAMINE
IMIDAZOLES
MAMMALS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANOLEPTIC PROPERTIES
ORGANS
RADIATION DOSES
RADIATION EFFECTS
RATS
REFLEXES
RODENTS
SENSE ORGANS
TASTE BUDS
VERTEBRATES