Attenuation of radiation- and drug-induced conditioned taste aversions following area postrema lesions in the rat

Journal Article · Tue Feb 01 04:00:00 EST 1983 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3575994· OSTI ID:5681959

Rabin, B M ^[1]; Hunt, W A; Lee, J

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1. Univ. of Maryland Baltimore County, Catonsville

The effects of lesions of the area postrema on the acquisition of radiation- and drug-induced (histamine and lithium chloride) conditioned taste aversions were investigated. The results indicated that area postrema lesions caused a significant attenuation of the aversion produced by pairing a novel sucrose solution with radiation (100 rad) or drug injection. Further, the area postrema lesions produced a similar level of attenuation of the taste aversion in all three treatment conditions. The results are discussed in terms of the implications of this finding for defining the mechanisms by which exposure to ionizing radiation can lead to the acquisition of a conditioned taste aversion.

• OSTI ID: 5681959
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 93:2; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METAL COMPOUNDS
AMINES
ANIMALS
AVOIDANCE
AZOLES
BEHAVIOR
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CHLORIDES
CHLORINE COMPOUNDS
COBALT 60
COBALT ISOTOPES
DATA
ELECTROMAGNETIC RADIATION
EXPERIMENTAL DATA
GAMMA RADIATION
HALIDES
HALOGEN COMPOUNDS
HETEROCYCLIC COMPOUNDS
HISTAMINE
IMIDAZOLES
INFORMATION
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
IONIZING RADIATIONS
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LITHIUM CHLORIDES
LITHIUM COMPOUNDS
LITHIUM HALIDES
MAMMALS
MEDICINE
MINUTES LIVING RADIOISOTOPES
NERVOUS SYSTEM
NUCLEI
NUMERICAL DATA
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
RADIATION EFFECTS
RADIATIONS
RADIOINDUCTION
RADIOISOTOPES
RATS
RODENTS
SURGERY
VERTEBRATES
YEARS LIVING RADIOISOTOPES