Methods of assessment of absorbed dose in clinical use of radionuclides

Book · Mon Jan 01 04:00:00 EST 1979

OSTI ID:6195303

The purpose of this publication is to extend the ICRU reports into the area of medical internal radiation doses. The report proposes the use of the formalism of Loevinger and Berman that has become familiar in the MIRD publications. The ICRU report refers often to the MIRD Committee works. The report sets out the basic concepts and formulae of internal dosimetry. It then gives an appraisal of the methods for obtaining biological data, ranging from animal distributions through scanning methods. It summarizes the procedures used in estimating absorbed dose, and six examples of dose calculations of increasing complexity are explained in an appendix. The last section of the text briefly mentions problems and recommendations. Among these are the increase in labor required to do these calculations and the need for more and better biological data. It urges the standard tabulation of data to allow for all the sources of internal dose and requests the reporting of original retention data for radiopharmaceuticals rather than just the calculations of radiation dose.

• OSTI ID: 6195303
• Country of Publication: United States
• Language: English

Related Subjects

550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
560161* -- Radionuclide Effects
Kinetics
& Toxicology-- Man
560171 -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Man-- (-1987)
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL MODELS
CALCULATION METHODS
COUNTING TECHNIQUES
DOSIMETRY
DRUGS
ICRU
INTERNATIONAL ORGANIZATIONS
LABELLED COMPOUNDS
PHARMACOLOGY
RADIATION DOSE DISTRIBUTIONS
RADIOISOTOPE SCANNING
RADIONUCLIDE KINETICS
RADIOPHARMACEUTICALS
RECOMMENDATIONS
RETENTION