The MIRD method of estimating absorbed dose

Conference · Tue Jan 01 04:00:00 EST 1991

OSTI ID:5915860

Weber, D A

The estimate of absorbed radiation dose from internal emitters provides the information required to assess the radiation risk associated with the administration of radiopharmaceuticals for medical applications. The MIRD (Medical Internal Radiation Dose) system of dose calculation provides a systematic approach to combining the biologic distribution data and clearance data of radiopharmaceuticals and the physical properties of radionuclides to obtain dose estimates. This tutorial presents a review of the MIRD schema, the derivation of the equations used to calculate absorbed dose, and shows how the MIRD schema can be applied to estimate dose from radiopharmaceuticals used in nuclear medicine.

• Research Organization: Brookhaven National Lab., Upton, NY (USA)
• Sponsoring Organization: DOE; USDOE, Washington, DC (USA)
• DOE Contract Number: AC02-76CH00016
• OSTI ID: 5915860
• Report Number(s): BNL-45932; CONF-910763--1; ON: DE91010343
• Country of Publication: United States
• Language: English

Related Subjects

550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
560161* -- Radionuclide Effects
Kinetics
& Toxicology-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
DISTRIBUTION
DOSES
DRUGS
EQUATIONS
LABELLED COMPOUNDS
MEDICINE
METABOLISM
NUCLEAR MEDICINE
RADIATION DOSES
RADIOPHARMACEUTICALS
TISSUE DISTRIBUTION