Intestinal transport of manganese from human milk, bovine milk and infant formula in rats

Journal Article · Mon Dec 10 04:00:00 EST 1984 · Life Sci.; (United States)

DOI:https://doi.org/10.1016/0024-3205(84)90449-1· OSTI ID:6093557

Chan, W Y; Bates, Jr, J M; Rennert, O M; Mahmood, A; Torres-Pinedo, R

The transport of manganese from extrinsically labeled human milk, bovine milk and infant formula was studied by the everted intestinal sac method. Tissue/mucosal flux data indicated that transport of manganese into the intestinal tissue was significantly greater with bovine milk and formula than from human milk. Similarly, the total flux of manganese from the mucosal to serosal surface was less when human milk was used. Smaller molecular weight manganese binding ligands isolated from the milk samples enhanced the mucosal to tissue movement of manganese as contrasted to the higher molecular weight manganese binding ligands. Most significantly the data suggest that the transport and uptake of manganese is less in the presence of human milk and its isolated manganese fractions than it is in bovine milk or infant formula. 15 references, 3 tables.

• Research Organization: Univ. of Oklahoma Health Sciences Center, Oklahoma City
• OSTI ID: 6093557
• Journal Information: Life Sci.; (United States), Journal Name: Life Sci.; (United States) Vol. 35:24; ISSN LIFSA
• Country of Publication: United States
• Language: English

Related Subjects

551001 -- Physiological Systems-- Tracer Techniques
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ANIMALS
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CATTLE
CHEMICAL ANALYSIS
CHEMICAL BONDS
DATA
DAYS LIVING RADIOISOTOPES
DIGESTIVE SYSTEM
DOMESTIC ANIMALS
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
EXPERIMENTAL DATA
FOOD
GASTROINTESTINAL TRACT
INFORMATION
INTERMEDIATE MASS NUCLEI
INTESTINAL ABSORPTION
INTESTINES
ISOTOPE APPLICATIONS
ISOTOPES
LIGANDS
MAMMALS
MAN
MANGANESE
MANGANESE 54
MANGANESE ISOTOPES
MATERIALS
METALS
MILK
NUCLEI
NUMERICAL DATA
ODD-ODD NUCLEI
ORGANS
PRIMATES
RADIOISOTOPES
RATS
RODENTS
RUMINANTS
SPECIES DIVERSITY
TRACER TECHNIQUES
TRANSITION ELEMENTS
UPTAKE
VERTEBRATES