Supercritical-fluid extraction and chromatography-mass spectrometry for analysis of mycotoxins
The use of direct supercritical-fluid injection-mass spectrometry for the rapid analysis of mycotoxins of the tricothecene group is demonstrated. A solution containing diacetoxyscirpenol or T-2 toxin is injected into a fluid consisting primarily of pentane or carbon dioxide and is rapidly brought to supercritical conditions. Direct injection of the fluid stream into a chemical ionization source allows thermally labile compounds to be analyzed. Under these conditions trichothecene mass spectra showing significant (M + 1)/sup +/ ions and distinctive fragmentation patterns are obtained. Detection limits are in the subnanogram range. Direct analysis from complex substrates using selective supercritical-fluid extraction is proposed. 4 figures.
- Research Organization:
- Pacific Northwest Lab., Richland, WA (USA)
- DOE Contract Number:
- AC06-76RL01830
- OSTI ID:
- 6053543
- Report Number(s):
- PNL-SA-10617; CONF-8210157-1; ON: DE83013745
- Resource Relation:
- Conference: Association of Official Analytical Chemists meeting, Washington, DC, USA, 25 Oct 1982
- Country of Publication:
- United States
- Language:
- English
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Supercritical fluid extraction and direct fluid injection mass spectrometry for the determination of trichothecene mycotoxins in wheat samples
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Related Subjects
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
TOXINS
MASS SPECTROSCOPY
CARBON DIOXIDE
EXPERIMENTAL DATA
EXTRACTION
HIGH PRESSURE
MEDIUM TEMPERATURE
PENTANE
QUANTITATIVE CHEMICAL ANALYSIS
ALKANES
ANTIGENS
CARBON COMPOUNDS
CARBON OXIDES
CHALCOGENIDES
CHEMICAL ANALYSIS
DATA
HYDROCARBONS
INFORMATION
MATERIALS
NUMERICAL DATA
ORGANIC COMPOUNDS
OXIDES
OXYGEN COMPOUNDS
SEPARATION PROCESSES
SPECTROSCOPY
TOXIC MATERIALS
400104* - Spectral Procedures- (-1987)