Supercritical fluid extraction and direct fluid injection mass spectrometry for the determination of trichothecene mycotoxins in wheat samples

Journal Article · Wed Oct 01 04:00:00 EDT 1986 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac00125a015· OSTI ID:5347085

Kalinoski, H T; Udseth, H R; Wright, B W; Smith, R D

The application of on-line supercritical fluid extraction with chemical ionization mass spectrometry and collision induced dissociation tandem mass spectrometry for the rapid identification of parts-per-million levels of several trichothecene mycotoxins is demonstrated. Supercritical carbon dioxide is shown to allow identification of mycotoxins with minimum sample handling in complex natural matrices (e.g., wheat). Tandem mass spectrometry techniques are employed for unambiguous identification of compounds of varying polarity, and false positives from isobaric compounds are avoided. Capillary column supercritical fluid chromatography-mass spectrometry of a supercritical fluid extract of the same sample was also performed and detection limits in the parts-per-billion range appear feasible.

• Research Organization: Battelle, Pacific Northwest Labs., Richland, WA
• OSTI ID: 5347085
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 58:12; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400102 -- Chemical & Spectral Procedures
400104* -- Spectral Procedures-- (-1987)
400105 -- Separation Procedures
ANTIGENS
BACTERIA
BLOOD VESSELS
BODY
CAPILLARIES
CARBON COMPOUNDS
CARBON DIOXIDE
CARBON OXIDES
CARDIOVASCULAR SYSTEM
CEREALS
CHALCOGENIDES
CHEMICAL ANALYSIS
CHROMATOGRAPHY
DATA
EXPERIMENTAL DATA
FLUIDS
GRASS
INFORMATION
INJECTION
INTAKE
MASS SPECTROSCOPY
MATERIALS
MICROORGANISMS
MYCOBACTERIUM
NUMERICAL DATA
ORGANS
OXIDES
OXYGEN COMPOUNDS
PLANTS
POLAR COMPOUNDS
QUANTITATIVE CHEMICAL ANALYSIS
SEPARATION PROCESSES
SPECTROSCOPY
SUPERCRITICAL FLUID CHROMATOGRAPHY
TOXIC MATERIALS
TOXINS
TRACE AMOUNTS
WHEAT