Effect of dietary lead on performance, tissue mineral composition and lead absorption in sheep

Journal Article · Thu Jan 01 04:00:00 EST 1976 · J. Anim. Sci.; (United States)

OSTI ID:6027086

Fick, K R; Ammerman, C B; Miller, S M; Simpson, C F; Loggins, P E

Twenty wether lambs were individually fed for 84 days to study the effect of dietary lead on performance and mineral composition of selected tissues. The treatments included 0, 10, 100, 500 and 1000 ppm supplemental lead as lead acetate added to a practical diet. Increased dietary lead did not affect feed consumption, weight gain or feed conversion ratio. Hemoglobin, hematocrit and blood lead were not affected by dietary treatments. Lead concentrations were higher (P < .01) in liver, bone, brain and spleen when 500 and 1000 ppm dietary lead was fed. High dietary lead also resulted in higher (P < .05) lead concentrations in kidney, heart and muscle. As dietary lead increased, zinc levels in heart and brain increased (P < .01) and iron levels in the brain decreased (P < .01). In a second study, six sheep each were assigned to diets containing either 50 or 1000 ppm supplemental lead, respectively, to determine the effect of dietary lead on nutrient digestibility, nitrogen and lead balance. Supplemental lead did not affect nutrient digestibility or nitrogen balance. More lead was absorbed and retained with the greater intake but the percentage of apparent absorption and net retention of lead was not significantly different among treatments.

• Research Organization: Univ. of Florida, Gainesville
• OSTI ID: 6027086
• Journal Information: J. Anim. Sci.; (United States), Journal Name: J. Anim. Sci.; (United States) Vol. 42:2; ISSN JANSA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism &amp; Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
DISTRIBUTION
DOMESTIC ANIMALS
ELEMENTS
GROWTH
LEAD
MAMMALS
METALS
RUMINANTS
SHEEP
TISSUE DISTRIBUTION
TOXICITY
UPTAKE
VERTEBRATES