Synthesis of radiopharmaceuticals containing short-lived radionuclides: Progress report, March 1, 1987-February 28, 1988

Technical Report · Tue Sep 01 04:00:00 EDT 1987

OSTI ID:5995261

Kabalka, G W

The objective is the creation of new methods for introducing short-lived isotopes into agents for use in diagnostic nuclear medicine. Focus is on the design of new molecular architecture as opposed to the application of known reactions to the synthesis of specific radiopharmaceuticals. The new technology is utilized in nuclear medicine research at the University of Tennessee Medical Imaging Center and in collaboration with colleagues at other DOE facilities. The program provides training for students in the scientific aspects of nuclear medicine. The academic nature of the program facilitates collaborative interactions with other DOE nuclear medicine programs and helps to insure the continued availability of skilled scientists dedicated to the advancement of nuclear medicine. 70 refs., 9 figs.

• Research Organization: Tennessee Univ., Knoxville (USA). Dept. of Chemistry
• DOE Contract Number: FG05-86ER60434
• OSTI ID: 5995261
• Report Number(s): DOE/ER/60434-2; ON: DE88000162
• Country of Publication: United States
• Language: English

Related Subjects

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
400703 -- Radiochemistry & Nuclear Chemistry-- Radioisotope Production
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
560161 -- Radionuclide Effects
Kinetics
& Toxicology-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALCOHOLS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BUTANOLS
CARBON 11
CARBON ISOTOPES
CHEMICAL PREPARATION
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DOCUMENT TYPES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
EVEN-ODD NUCLEI
HOURS LIVING RADIOISOTOPES
HYDROXY COMPOUNDS
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LIGHT NUCLEI
MAMMALS
MAN
MEDICINE
MINUTES LIVING RADIOISOTOPES
NITROGEN 13
NITROGEN ISOTOPES
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
OXYGEN 15
OXYGEN ISOTOPES
POSITRON COMPUTED TOMOGRAPHY
PRIMATES
PROGRESS REPORT
RADIOISOTOPES
RADIONUCLIDE KINETICS
RADIOPHARMACEUTICALS
SAMPLE PREPARATION
SYNTHESIS
TECHNETIUM ISOTOPES
TOMOGRAPHY
VERTEBRATES