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Effect of low-dose-rate irradiation on the division potential of cells in vitro. V. Human skin fibroblasts from donors with a high risk of cancer. [/sup 60/Co]

Journal Article · · J. Natl. Cancer Inst.; (United States)
OSTI ID:5944692
Skin fibroblasts from normal donors, donors with ataxia-telanglectasia or Fanconi's anemia, and from 1 cancer patient were treated with repeated ..gamma.. radiation at about 16 rads per hour. The remaining division potential of all fibroblasts, except for the Fanconi's anemia cells, was reduced to different extents by radiation. The growth potential of Fanconl's anemia cells was increased in all the irradiated cultures. The increase was 54% in the group that survived the longest. These results were identical to those obtained with fibroblasts from certain species that have a high probability of transformation.
Research Organization:
Inst. de Cancerologie et d'Immunogenetique (INSERM), Villejuif, France
OSTI ID:
5944692
Journal Information:
J. Natl. Cancer Inst.; (United States), Journal Name: J. Natl. Cancer Inst.; (United States) Vol. 63:1; ISSN JNCIA
Country of Publication:
United States
Language:
English

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