Controlled exposures of human volunteers to sulfate aerosols. Health effects and aerosol characterization
A study of possible acute adverse health effects of sulfate aerosols was undertaken through controlled exposures of volunteer human subjects. Both healthy and asthmatic adult men were exposed for 2-hour periods (with intermittent exercise) to ammonium sulfate, ammonium bisulfate, and sulfuric acid of particle size distributions and concentrations intended to simulate worst case exposures during Los Angeles smog episodes. Lung function tests were performed by the subjects on entering and before exiting from a carefully controlled environmental chamber. Subject symptoms were evaluated in a standardized manner. Aerosol concentrations and size distributions were determined by an on-line computer/aerometric monitoring system; gravimetric and chemical analyses were performed on impactor and total filter samples after test exposures. Little or no evidence of adverse health effects was found from 2-hour multiple-day exposures to any of the compounds at worst case ambient concentrations.
- Research Organization:
- Environmental Health Service, Downey, CA
- OSTI ID:
- 5930302
- Journal Information:
- Am. Rev. Respir. Dis.; (United States), Journal Name: Am. Rev. Respir. Dis.; (United States) Vol. 120:2; ISSN ARRDA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
AEROSOL MONITORING
AEROSOLS
AMMONIA
ASTHMA
BIOLOGICAL EFFECTS
CALIFORNIA
COLLOIDS
COMPARATIVE EVALUATIONS
DISEASES
DISPERSIONS
DISTRIBUTION
HYDRIDES
HYDROGEN COMPOUNDS
INORGANIC ACIDS
LOS ANGELES
MONITORING
NITROGEN COMPOUNDS
NITROGEN HYDRIDES
NORTH AMERICA
OXYGEN COMPOUNDS
PARTICLE SIZE
RESPIRATORY SYSTEM DISEASES
SIZE
SOLS
SULFATES
SULFUR COMPOUNDS
SULFURIC ACID
USA
WESTERN REGION