Measurements of the distribution of technetium-99m sulfur colloid and technetium-99m HEDP in normal humans
Journal Article
·
· Med. Phys.; (United States)
Technetium-99m sulfur colloid and technetium-99m hydroxyethylidene diphosphonate (HEDP) are two radiopharmaceuticals that have been widely used in nuclear medicine. Radiation dose estimates for both materials have been published in the literature and are found in the package inserts of the commercial kits. However, these estimates were made without the benefit of quantitative human organ uptake data. Estimates of absorbed radiation dose to the kidneys differ by nearly a factor of 6 between the two calculations for HEDP. The results of this study are in agreement with the lower previous estimate. Other than that one exception, agreement of the previous estimates with the measurements reported here is surprisingly good.
- Research Organization:
- National Center for Devices and Radiological Health, Food and Drug Administration, Cincinnati, Ohio
- OSTI ID:
- 5895121
- Journal Information:
- Med. Phys.; (United States), Journal Name: Med. Phys.; (United States) Vol. 10:1; ISSN MPHYA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Measurements of the distribution of technetium-99m sulfur colloid and technetium-99m HEDP in normal humans
Chromatographic characterization and biological behavior of technetium diphosphonate radiopharmaceuticals
Tc-99m HMDP (Hydroxymethylene diphosphonate): a radiopharmaceutical for skeletal and acute myocardial infarct imaging. I. synthesis and distribution in animals. [Rats, dogs]
Journal Article
·
Fri Dec 31 23:00:00 EST 1982
· Med. Phys.; (United States)
·
OSTI ID:6514465
Chromatographic characterization and biological behavior of technetium diphosphonate radiopharmaceuticals
Thesis/Dissertation
·
Wed Dec 31 23:00:00 EST 1986
·
OSTI ID:7191022
Tc-99m HMDP (Hydroxymethylene diphosphonate): a radiopharmaceutical for skeletal and acute myocardial infarct imaging. I. synthesis and distribution in animals. [Rats, dogs]
Conference
·
Wed Oct 01 00:00:00 EDT 1980
· J. Nucl. Med.; (United States)
·
OSTI ID:6861338
Related Subjects
550601 -- Medicine-- Unsealed Radionuclides in Diagnostics
560171* -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Man-- (-1987)
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COLLOIDS
DISPERSIONS
DOSES
DRUGS
ELEMENTS
ESTERS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KIDNEYS
LABELLED COMPOUNDS
NONMETALS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
PHOSPHORIC ACID ESTERS
RADIATION DOSES
RADIOCOLLOIDS
RADIOISOTOPES
RADIOPHARMACEUTICALS
SULFUR
TECHNETIUM 99
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
560171* -- Radiation Effects-- Nuclide Kinetics & Toxicology-- Man-- (-1987)
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COLLOIDS
DISPERSIONS
DOSES
DRUGS
ELEMENTS
ESTERS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KIDNEYS
LABELLED COMPOUNDS
NONMETALS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC PHOSPHORUS COMPOUNDS
ORGANS
PHOSPHORIC ACID ESTERS
RADIATION DOSES
RADIOCOLLOIDS
RADIOISOTOPES
RADIOPHARMACEUTICALS
SULFUR
TECHNETIUM 99
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES