Effects of benzo(a)pyrene on Friend viral leukemogenesis in B10SJF mice

Journal Article · Sat Jan 01 04:00:00 EST 1983 · Proc. Soc. Exp. Biol. Med.; (United States)

DOI:https://doi.org/10.3181/00379727-172-41524· OSTI ID:5893786

Raikow, R B; Okunewick, J P; Buffo, M J; Jones, D L

A single intraperitoneal injection of benzo(a)pyrene (BP) given 1, 2, or 3 days before an ip injection of Friend leukemia virus (FLV) significantly increased the leukemogenic effect of the virus in B10SJF mice. These hybrids are the offspring of C57BL/10 females and SJL/J males and are highly resistant to FLV leukemogenesis when the virus is injected alone.

• Research Organization: Allegheny-Singer Research Corp., Pittsburgh, PA
• DOE Contract Number: AC02-78EV04800
• OSTI ID: 5893786
• Journal Information: Proc. Soc. Exp. Biol. Med.; (United States), Journal Name: Proc. Soc. Exp. Biol. Med.; (United States) Vol. 172:1; ISSN PSEBA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
AROMATICS
AUGMENTATION
BENZOPYRENE
BIOLOGICAL EFFECTS
CARCINOGENESIS
CONDENSED AROMATICS
HYDROCARBONS
INFECTIVITY
LEUKEMIA VIRUSES
MAMMALS
MICE
MICROORGANISMS
ONCOGENIC VIRUSES
ORGANIC COMPOUNDS
PARASITES
PATHOGENESIS
RODENTS
VERTEBRATES
VIRUSES