Regulation of natural killer activity of lymphocytes from normal subjects and patients with chronic lymphatic leukemia by interaction between T and non-T cells

Journal Article · Sat Aug 01 04:00:00 EDT 1987 · Bull. Exp. Biol. Med. (Engl. Transl.); (United States)

DOI:https://doi.org/10.1007/BF00840562· OSTI ID:5785280

Khonina, N A; Shubinskii, G Z; Lozovoi, V P

The authors study the effect of culture of human cells on functional activity of natural killer cells and investigate the possible mechanisms of regulation of natural killer activity by acting on cytodifferentiation of lymphocytes in normal subjects and in patients with the B-cell variant of chromic lymphatic leukemia. To estimate natural killer cell function, a membranotoxic test was carried out, using cells of the transplantable line K-562, labeled with /sup 3/H-uridine as the targets.

• Research Organization: Institute of Clinical Immunology, Novosibirsk, USSR
• OSTI ID: 5785280
• Journal Information: Bull. Exp. Biol. Med. (Engl. Transl.); (United States), Journal Name: Bull. Exp. Biol. Med. (Engl. Transl.); (United States) Vol. 103:3; ISSN BEXBA
• Country of Publication: United States
• Language: English

Related Subjects

550301* -- Cytology-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ANIMAL CELLS
ANIMALS
AZINES
BIOCHEMISTRY
BIOLOGICAL FUNCTIONS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CELL CULTURES
CELL DIFFERENTIATION
CELL KILLING
CHEMISTRY
CONNECTIVE TISSUE CELLS
CYTOCHEMISTRY
DISEASES
FUNCTIONS
HEMIC DISEASES
HETEROCYCLIC COMPOUNDS
HYDROXY COMPOUNDS
IMMUNOASSAY
IMMUNOLOGY
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
LABELLING
LEUKEMIA
LEUKOCYTES
LYMPHOCYTES
MAMMALS
MAN
MATERIALS
NEOPLASMS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PATIENTS
PRIMATES
PYRIMIDINES
RADIOACTIVITY
RADIOASSAY
RADIOIMMUNOASSAY
RADIOIMMUNOLOGY
RIBOSIDES
SOMATIC CELLS
TRACER TECHNIQUES
TRITIUM COMPOUNDS
TUMOR CELLS
URACILS
URIDINE
VERTEBRATES