Effect of errors in reangulation on planar and tomographic thallium-201 washout profile curves

Journal Article · Sun Dec 01 04:00:00 EST 1985 · J. Nucl. Med.; (United States)

OSTI ID:5678937

Lancaster, J L; Starling, M R; Kopp, D T; Lasher, J C; Blumhardt, R

Cardiac phantom studies were performed with and without a defect present to test the hypothesis that myocardial 201TI quantitative circumferential washout profile curves calculated from planar and rotating slant hole (RSH) collimator tomographic images are equally affected by errors in axial repositioning. Simulated stress images were acquired with the long axis of the phantom perpendicular to the camera surface and redistribution images were acquired to represent 50% 201TI washout with axial repositioning errors relative to the stress position ranging from 0 to 20 degrees in 5 degrees increments. There was a decrease in the 201TI washout profile curves compared to that expected (50%) in the wall tilted away from the camera surface, and a reciprocal increase in the 201TI washout profile curves in the wall tilted towards the camera surface for both imaging techniques whether a lesion was present or not. This effect became more pronounced as the error in axial repositioning was increased for both the planar (p less than 0.001) and the RSH tomographic (p less than 0.001) techniques. However, the deviation of the 201TI washout profile curves from that expected (50%) was greater for the planar imaging technique with or without a lesion (p less than 0.05 to 0.001). Thus, we conclude that 201TI quantitative circumferential washout profile curves calculated using this tomographic imaging technique are less affected by errors in axial repositioning than those calculated using an equivalent projection by standard planar imaging methods. These data emphasize the importance which must be placed on the repositioning of patients to obtain valid 201TI washout profile curves for the detection and localization of coronary artery disease.

• OSTI ID: 5678937
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 12; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
COLLIMATORS
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
ELECTRON CAPTURE RADIOISOTOPES
ERRORS
HEART
HEAVY NUCLEI
IMAGES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MOCKUP
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PHANTOMS
POSITIONING
RADIOISOTOPES
SECONDS LIVING RADIOISOTOPES
STRUCTURAL MODELS
THALLIUM 201
THALLIUM ISOTOPES
TOMOGRAPHY