Effect of zinc source and picolinic acid on /sup 65/Zn uptake in an in vitro continuous-flow perfusion system for pig and poultry intestinal segments

Journal Article · Thu Oct 01 04:00:00 EDT 1987 · J. Nutr.; (United States)

OSTI ID:5664051

Hill, D A; Peo, Jr, E R; Lewis, A J

Twenty weanling pigs and fourteen 9-wk-old broiler chickens were used in three continuous-flow in vitro perfusion experiments using noneverted intestinal sacs to 1) determine differences in /sup 65/Zn absorption due to location within the intestinal tract, 2) evaluate /sup 65/Zn uptake from ZnCl/sub 2/ and Zn-methionine (ZnMet) with or without added picolinic acid (PA) in pig intestinal sacs and 3) evaluate /sup 65/Zn uptake from ZnCl/sub 2/ and ZnMet in chicken intestinal sacs. No differences in /sup 65/Zn uptake due to gut segment position were observed in the pigs. A Zn source x PA interaction was observed for /sup 65/Zn uptake into the pig gut tissue and for /sup 65/Zn uptake to the serosal side of the gut sacs. Total /sup 65/Zn absorption in the pig gut sacs from the two Zn sources was not different, but the addition of a 5 M ratio of PA to Zn depressed /sup 65/Zn absorption. No differences were observed in total /sup 65/Zn absorption or /sup 65/Zn uptake in poultry gut sac tissue. There was, however, greater uptake of /sup 65/Zn from ZnCl/sub 2/ to the serosal side of the sacs than from ZnMet. The data indicate that /sup 65/Zn from ZnCl/sub 2/ and ZnMet is similar in total absorption and that the addition of PA depresses Zn uptake.

• Research Organization: Univ. of Nebraska, Lincoln
• OSTI ID: 5664051
• Journal Information: J. Nutr.; (United States), Journal Name: J. Nutr.; (United States) Vol. 117:10; ISSN JONUA
• Country of Publication: United States
• Language: English

Related Subjects

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59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
AMINO ACIDS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BIRDS
BODY
CARBOXYLIC ACIDS
CHICKENS
CHLORIDES
CHLORINE COMPOUNDS
DAYS LIVING RADIOISOTOPES
DOMESTIC ANIMALS
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
ELEMENTS
EVEN-ODD NUCLEI
FOWL
HALIDES
HALOGEN COMPOUNDS
IN VITRO
INTERMEDIATE MASS NUCLEI
INTESTINAL ABSORPTION
ISOTOPE APPLICATIONS
ISOTOPES
LIGANDS
LIPOTROPIC FACTORS
MAMMALS
METALS
METHIONINE
NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
ORGANS
PERFUSED ORGANS
RADIOISOTOPES
SWINE
TRACER TECHNIQUES
UPTAKE
VERTEBRATES
ZINC
ZINC 65
ZINC CHLORIDES
ZINC COMPOUNDS
ZINC HALIDES
ZINC ISOTOPES